ESCI Council: Gabriella Garruti, Marcel Twickler
Invited Organizer(s): Rita Machado de Oliveira, Paulo Matafome
Meeting room: 

Wednesday, 3 June 

13.30-15.00 Session 1.1  Diabesity In 2035: Risk, Prevention and Precision Therapy
Chair: Raquel Soares (Porto, Portugal)

13:30-13:50 Evolution of diabetes prevalence and complications João Raposo (Lisbon, Portugal)

13:50-14:10 Diabetes in women: the overlooked dimension Didac Mauricio (Barcelona, Spain)

14:10-14:30 Clinical challenges in obesity Inês Figueiredo (Lisbon, Portugal)

14.30-14.45 The Global South is underrepresented in clinical type 1 diabetes research Amar Van Laar

Coffee-break


15.30-17.00 Session 1.2  The Gut as a Metabolic Command Center: Microbiota, Hormones and Extracellular Vesicles
Chair: Gabriella Garruti (Bari, Italy)

15.30-16:00 Extracellular vesicles… Rita Machado de Oliveira (Lisbon, Portugal)

16.00-16.30 Local and systemic sequelae of enterohepatic circulation. The bile acid perspective Piero Portincasa (Bari, Italy)

16.30-16.45 Effect of lifestyle changes and weight loss on intestinal barrier and hepatic sinusoidal endothelial function in patients with MASLD Jerlin Johnbritto

16.45-17.00 Integrated phenotyping of the gut-platelet-liver axis in the progression of MASLD-related chronic liver disease Alessandra Pistillo

Opening ceremony

Opening lecture

Welcome drink


Thursday, 4 June 

08.30-10.00 Session 1.3 Adipose Tissue as an Endocrine and Immune Organ: From White to Brown to Beige & Beyond
Chair: Marcel Twickler (Belgium)

08.30-08.50 Energy balance (dys) regulation in the adipose tissue Paulo Matafome (Lisbon, Portugal)

08.50-09.10 TBC Amalia Gastaldelli (Pisa, Italy)

09.10-09.30 Obesity staging and adipose tissue health in clinical practice Mariana Monteiro

09.30-09.45  Non-invasive assessment of meal [U-[sup]13[/sup]C]glucose conversion to hepatic glycine in T2D/MASLD patients using p-amino benzoic acid Cristina Barosa

09.45-10.00 A metabotype approach as a potential scalable strategy to deliver targeted dietary recommendations to elderly (NUTRIMET) Bárbara Tello Durán

10:00 – 11:00 Coffee-break & Poster Session (Group A)

11.00-12.30 Session 1.4  Rethinking Organ Boundaries in Metabolic Disease: What Are We Still Missing?
Chair: Susan Weihrauch-Blüher (Halle, Germany)
Chair: Rita Machado de Oliveira (Lisbon, Portugal)

11.00-11.20 Liver, MASLD…Rui Castro (Lisbon, Portugal)

11.20-11.40 The gut-adipose-brain axis and the microbiome in obesity and diabetes Gabriella Garruti (Bari, Italy)

11.40-12.00 Organ crosstalk and obesity complications: does gender matters? Raquel Soares (Porto, Portugal)

12.00-12.15 Mediterranean Bioactives Compounds and Dopamine Modulate GLP-1 and PYY Expression and Secretion in Intestinal L-Cells Diana Sousa

13.30-14.30 Lunch & Poster Session (Group B)

14.30-16.00 Session 1.5  Sex, Life Stages and Intergenerational Metabolic Programming
Chair: Paulo Matafome (Lisbon, Portugal)

14.30-14.50 Endocrine control of sexual maturation in obesity Manuel Tena-Sempere (Cordoba, Spain)

14.50-15.10 Prolactin as a circadian messenger between atherometabolism and the brain Marcel Twickler (Antwerpen, Belgium)

15.10-15.30 Lactation as a Window for the Developmental Programming of Metabolic Syndrome Catalina Picó (Balearic Islands, Spain)

15.30-15.45 Preconception, Pregnancy, and Lactation in Women With Familial Hypercholesterolaemia: Clinical Challenges and Management Strategies Ilayda Kalkan

16.00-16.50 Round table: Hormonal, Metabolic, and Cancer Dynamics Across Women’s Life Transitions

16.30-17.30   Brief oral sessions and coffee-break

17.30-18.30   Satellite Symposium: Pas Gras

19.30            Congress dinner

Friday, 5 June 

09.00-10.30 Session 1.6  Rewiring Metabolism Through Lifestyle: Nutrition, Exercise and Circadian Rhythm
Chair: Silvio Buscemi (Palermo, Italy)

09.00-09.20 Diet along lifespan Claudia Marques (Lisbon, Portugal)

09.20-09.40 Physical exercise, circadian rhythms and metabolism João Magalhães (Lisbon, Portugal)

09.40-10.00 Nutrition in childhood obesity Susan Weihrauch-Blüher (Halle, Germany)

10.00-10.15 Liver derived extracellular vesicles modulate skeletal muscle insulin response and glucose homeostasis in prediabetes Pedro Ribeiro


10.30-11.30 Coffee-break & Poster Session (Group C)


11.30-13.00 Session 1.7  From Bench to Breakthroughs: Future Therapeutic Frontiers in Metabolic Disorders
Chair: Rita Machado de Oliveira (Lisbon, Portugal)

11.30-11.50 From the ABCD of Obesity to a new framework for the diagnosis and management of obesity in adults Gema Frühbeck Martínez (Navarra, Spain)

11.50-12.10 New therapeutic targets Cyriele Caussy (Lyon, France)

12.10-12.30 Pleiotropic effects of incretin-based therapies: from organ-specific mechanisms to a systemic cardio–hepato–metabolic–renal paradigm Silvio Buscemi (Palermo, Italy)

12.30-12.45 Optimization and expansion of the Edmonton Obesity Staging System framework Amar Van Laar

12. 45-13.00 Multi-Omics Signatures of Circulating Exerkines Predict Cardiorespiratory Fitness Adaptations in Individuals With Prediabetes Candela Diaz


13.00-14:00 Lunch & Poster Session (Group D)

13.00-14.00 Lunch & Poster Session (Group D)

14:00-14:30 European Journal Clinical Investigation

14:30-15:30 ESCI Awards

15:30-16:30 Albert Struyvenberg Medal

16:30-17:00 Closing ceremony