Paulo Matafome holds a PhD in Biomedical Sciences (Faculty of Medicine, University of Coimbra, 2012). He is a Physiology Professor at the Coimbra Health School, Polytechnic University of Coimbra. He is also a Researcher at the Coimbra Institute of Clinical and Biomedical Research (iCBR), Faculty of Medicine of the University of Coimbra, and an integrated member of CIBB (research center of the University of Coimbra). He has published ~115 articles and 5 book chapters (h factor=32, Scopus.com). Supervised or co-supervised 14 PhD students, 23 MSc students, and 25 BSc Students. He currently is one of the co-coordinators of the Project PAS GRAS funded by the Horizon program—Cluster Health. His interests rely on the pathophysiology of metabolic diseases, namely obesity and type 2 diabetes, disclosing the mechanisms governing adipose tissue dysfunction in obesity and leading to insulin resistance, including the transgenerational risks of obesity.

Amalia Gastaldelli is Director of Research at the Institute of Clinical Physiology of National Research Council in Pisa, Italy, where she leads the Cardiometabolic Risk Group. She is also Adjunct Professor at UT Health San Antonio, TX, USA and at the Sant’Anna School in Pisa. Her research focuses on the pathophysiology of metabolic diseases, particularly MASLD, obesity, and type 2 diabetes, with emphasis on metabolic fluxes and hormone action. She is President of the European MASLD Study Group (EASD) and of EGIR-European Group for Insulin Resistance affiliated to EASD. She has served on international committees for clinical guidelines on MASLD/NAFLD and diabetes (EASL–EASD–EASO; IDF).

Mariana P. Monteiro is a medical doctor, Consultant in Endocrinology and Full Professor of Medicine at the School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Portugal. Mariana P. Monteiro's professional activities are dedicated to clinical practice, medical education, and academic research. Her research is focused on Diabetes, Obesity and Reproductive Endocrinology in a clinical and translational perspective, leading an interdisciplinary working group that uses a variety of molecular and clinical approaches, including clinical trials, to understand how energy and glucose homeostasis are regulated and can be retuned through medical interventions to target cardio-renal-metabolic non-communicable diseases.