I am a biomedical scientist with an internationally trained academic trajectory spanning aging, neurodegeneration, and metabolic diseases. My research focuses on the concept that metabolic diseases arise from dysregulated systemic signaling networks, with extracellular vesicles (EVs) acting as conserved and biologically active mediators of inter-organ communication.

Highly Cited Researcher in the field of Cross-Field – 2024 (www.webofscience.com/wos/author/record/1108721) ORCID: orcid.org/0000-0001-5359-1471 Email piero.portincasa@uniba.it Pubmed pubmed.ncbi.nlm.nih.gov/?term=portincasa+piero&sort=date Google Scholar scholar.google.com/citations?user=Ra8V2JIAAAAJ&hl=en WOS (Highly Cited Award Recipient) www.webofscience.com/wos/author/record/1108721 Piero Portincasa is full professor of internal medicine, chief of Division of Internal Medicine and vice-director of Department of Precision and Regenerative Medicine and Ionian Area at University of Bari “Aldo Moro” and Regional Hospital Policlinico, Bari, Italy. President of the residency program in Internal Medicine, director of the Regional Referral Center for Familial Mediterranean Fever (FMF). After training at Guy’s Hospital, University of London, UK, he became PhD at the University of Utrecht, Netherlands. Past-President and now Honorary Member of European Society of Clinical Investigation (ESCI) and national councillor, secretary of the Italian Society Internal Medicine, with Laurea H. Causa from “C. Davila” University, Bucharest, “I. Hatieganu” University, Cluj-Napoca, and University of Medicine and Pharmacy, Science and Technology, Targu-Mures, Romania. He is appointed with American Gastroenterological Fellowship (AGAF) (2020), and is the General Secretary of Community of Mediterranean Universities. He has been working in basic, translational, and clinical pathophysiological research of gastrointestinal and hepatobiliary tract for several years and is devoted to the comprehensive treatment of metabolic syndrome, hepatobiliary, gallstone disease, and liver steatosis. He is author of >600 full papers including original articles, books, book chapters, guidelines. He is Editor-in-Chief of the Springer Nature Journal Internal and Emergency Medicine (link.springer.com/journal/11739), official publication of the Italian Society of Internal Medicine (SIMI). Research interests include lipid metabolism, enterohepatic circulation, liver steatosis, metabolic disorders, microbiota, water transport, electrophysiology, functional ultrasonography, autoinflammatory disorders, lifestyles and nutrition in health and disease. He is an authority in the international field of internal medicine, gastroenterology, hepatology, rheumatology in close contact with undergraduate and postgraduate residents, PhD and post-doc trainees, many from abroad (India, Lebanon). He is teacher in internal medicine, geriatrics, semeiology, methodology of research and coordinator at the Bari English Medical Curriculum. Prof. Portincasa is totally dedicated to the advancement of Research, under-, post-graduate Education and Health care in the field of Gastroenterology and Internal Medicine with strong multidisciplinary approaches. This know how is being reversed in several international projects (i.e., Horizon, PRIMA etc.) dedicated to fulfil several aspects of the Sustainable Development Goals (SDGs) also in the Mediterranean basin and worldwide.