Endo-metabolism session-3: Complexities in liver and metabolic disorders
Tracks
Salone dei Dogi (Castello Boccanegra)
Thursday, May 22, 2025 |
9:00 - 10:30 |
Salone dei Dogi (Castello Boccanegra) |
Details
ORGANIZERS
ESCI Council: Paula Macedo and Marcin Krawczyk
ESCI YRC: Harshita Shanmugan
Invited Organizer(s): Federico Gatto, Edoardo Giannini and Piero Portincasa
Speaker
Gyorgy Baffy
Associate Professor
VA Boston Healthcare System, Harvard Medical School
MetALD: challenges of coexisting metabolic dysfunction and alcohol toxicity in the liver
9:00 - 9:30Biography
Dr. Baffy received his MD from the University of Debrecen. He trained in gastroenterology at the University of Michigan and the Brigham and Women’s Hospital. He is currently chief of gastroenterology at the VA Boston Healthcare System and associate professor at Harvard Medical School. His research focuses on metabolic dysfunction-associated steatotic liver disease (MASLD), including early portal hypertension and liver mechanobiology. He is involved in several multicenter studies addressing palliative care in end-stage liver disease, use of simvastatin in near-decompensated cirrhosis, and HCC surveillance. He published over 120 peer-reviewed papers and book chapters. He has been a member of various scientific review panels and journal editorial boards in the field. He was a Fulbright US Scholar in 2014. He is the recipient of the Madaus Prize from the Madaus Liver Foundation and the Hetényi Medal and Pro Optimo Merito in Gastroenterologia Award from the Hungarian Gastroenterological Association.
Sonia Najjar
Professor
Ohio University, Heritage College of Osteopathic Medicine
Linking MASH to chronic kidney disease
9:30 - 10:00Biography
Prof Sonia M. Najjar received her PhD degree from Stanford University Medical School studying the effect of diabetes on glucose absorption in enterocytes. As a post-doctoral fellow at the NIH where, she identified CEACAM1, a plasma membrane glycoprotein in the liver, as a substrate of the insulin receptor kinase on the sinusoidal domain. She has continued to focus on the role of CEACAM1 in insulin clearance and lipid metabolism since she began her independent career at the University of Toledo in 1994. She is best known for identifying a causative role for impaired insulin clearance in insulin resistance. She has also pioneered the finding that acutely insulin suppresses de novo lipogenesis in hepatocytes via phosphorylating CEACAM1. She has continued her research investigating the role of CEACAM1 in the pathogenesis of hepatic fibrosis. Prof Najjar has reached an international acclaim in metabolism and has published several high- impact papers in the field.
Joana F. Sacramento
Junior Researcher
Nova Medical School, Universidade Nova De Lisboa
Carotid Sinus Nerve Resection: A key to improve liver function in metabolic disease
10:00 - 10:15Biography
Laura Herrera
PhD Student
APDP – Diabetes Portugal
Serum paraoxonase 1 activity as a biomarker of early dysmetabolic stages and its link to liver disease
10:15 - 10:30Biography
Chair
Piero Portincasa
Head Division Internal Medicine
University of Bari Aldo Moro
Harshitha Shanmugam
Postdoctoral Clinical Researcher
University of Bari 'Aldo Moro', Policlinic Hospital
