I am a clinical hematologist with a strong background in high-level research since my medical studies at the University of Pavia. My main scientific contribution has been integrating single-cell transcriptomics and genomic sequencing to dissect hematological disease architecture and evolution after treatment. Under Prof. Mario Cazzola and Luca Malcovati, I explored SF3B1 mutations in myelodysplastic syndromes, now included in WHO/ICC classifications. At Würzburg University Hospital (2016-2019), I identified PSMB5 mutations as drivers of MM therapy resistance and uncovered RAS/RAF pathway dysregulation in CNS-MM. Recently, I described a novel immune escape mechanism in anti-BCMA CAR T therapy. Since 2019, I have been working with Prof. Niccolò Bolli at the University of Milan on the ERC-funded “BeCOMiNg” project, studying MM preclinical phases with multi-omics approaches. My research focuses on MM predictive models, integrating clinical practice with global collaborations to establish myself as an independent investigator.