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S12. Therapeutic Developments Session

Tracks
Room 3 | Crystal B/C
Thursday, June 18, 2026
14:00 - 16:00
Room 3 | Crystal B/C

Details

Chairs: Marie-Claude Potier and Renata Bartesaghi


Speaker

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Prof. Renata Bartesaghi
Professor Alma Mater
University of Bologna

First Panel: Treatment of cognitive deficits and regression in Down syndrome.

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Dr. Jonathan Santoro
Director of Neuroimmunology
Children's Hospital Los Angeles and the Keck School of Medicine of the University of Southern California

New Frontiers: Early Industry Engagement in Rare Disease.

14:00 - 14:15
Erin Fromm

New Frotiers: Early Industry Engagement in Rare Disease

14:00 - 14:15
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Dr Laurent Meijer
President & CSO
Perha Pharmaceuticals

Phase 1 clinical trial of Leucettinib-21, a DYRK1A kinase inhibitor aiming at the treatment of Down syndrome, Alzheimer’s disease, and Parkinson’s disease.

14:15 - 14:30
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Dr. Floriana Costanzo
Bambino Gesù Children's Hospital, Rome

Transcranial Direct Current Stimulation to Enhance Cognition and Behavior in Down Syndrome: A Randomized, Placebo-Controlled Proof-of-Concept Study on Language Outcomes

14:30 - 14:45
Dr Marie-claude Potier
Director Of Research Cnrs
Paris Brain Institute, ICM

Second Panel: Treatment of Alzheimer’s disease in Down syndrome

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Jennifer Ann Zimmer
Eli Lilly and Company

Alzheimer’s Disease in Adults with Down Syndrome: Closing the Clinical Research Gap.

14:45 - 15:00
Patrick Kesslak
Alzheon Inc.

Valiltramiprosate Reduced ARIA Rates in Phase 3 Study of APOE4/4 Subjects with Early AD: Implications to Down syndrome

15:00 - 15:15
Mr. Charlie Grieser
Alamar Biosciences

Decoding Alzheimer’s Progression and Neuroinflammation in Down Syndrome Through Ultra-Sensitive Biomarker Profiling.

15:15 - 15:30
Jack Walsh
OLINK

Accelerating impact with Thermo Fisher Olink proteomic solutions.

15:30 - 15:45
Dr Marie-claude Potier
Director Of Research Cnrs
Paris Brain Institute, ICM

Final discussion and conclusions

15:45 - 16:00
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