Agenda
Wednesday, June 17, 2026
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Room 1
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Room 2
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| 8:30 - 9:00 |
Registration
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| 9:00 - 10:30 | Opening Session | |
| 10:30 - 11:00 |
Break
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| 11:00 - 13:00 | S1. Brain Development and Connectivity Across the Lifespan in Down Syndrome: Insights from Cellular Mechanisms, Mouse Models, and Advanced Human MRI | S2. Eating, drinking, and swallowing challenges in Down syndrome: From clinical perspectives to insights from animal models |
| 13:00 - 14:00 |
Lunch and Networking
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| 14:00 - 15:00 | NDSS Charles J. Epstein Award for Early-Stage Investigators | |
| 15:00 - 16:00 | T21RS General Assembly | |
| 16:00 - 18:00 | S21. The INCLUDE Data Coordinating Center: a discovery accelerator for Down syndrome research | S5. Lifelong bone health in Down syndrome: new research, new directions |
| 19:00 - 22:00 |
Welcome Reception
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Room 3
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|---|---|
| 8:30 - 9:00 |
Registration
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| 9:00 - 10:30 | |
| 10:30 - 11:00 |
Break
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| 11:00 - 13:00 | S3.The DS-Connect® Registry and the INCLUDE Collaboration for Down Syndrome Progress (CDP): Two Transformative Tools to Accelerate Participant-Centered Research |
| 13:00 - 14:00 |
Lunch and Networking
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| 14:00 - 15:00 | |
| 15:00 - 16:00 | |
| 16:00 - 18:00 | S6. Innovative Engagement Methods and Communication Strategies for Promoting Down Syndrome Clinical Research Participation |
| 19:00 - 22:00 |
Welcome Reception
|
|
Room 1
|
|
|---|---|
| 8:30 - 9:00 |
Registration
|
| 9:00 - 10:30 | Opening Session |
| 10:30 - 11:00 |
Break
|
| 11:00 - 13:00 | S1. Brain Development and Connectivity Across the Lifespan in Down Syndrome: Insights from Cellular Mechanisms, Mouse Models, and Advanced Human MRI |
| 13:00 - 14:00 |
Lunch and Networking
|
| 14:00 - 15:00 | NDSS Charles J. Epstein Award for Early-Stage Investigators |
| 15:00 - 16:00 | T21RS General Assembly |
| 16:00 - 18:00 | S21. The INCLUDE Data Coordinating Center: a discovery accelerator for Down syndrome research |
| 19:00 - 22:00 |
Welcome Reception
|
|
Room 2
|
|
|---|---|
| 8:30 - 9:00 |
Registration
|
| 9:00 - 10:30 | |
| 10:30 - 11:00 |
Break
|
| 11:00 - 13:00 | S2. Eating, drinking, and swallowing challenges in Down syndrome: From clinical perspectives to insights from animal models |
| 13:00 - 14:00 |
Lunch and Networking
|
| 14:00 - 15:00 | |
| 15:00 - 16:00 | |
| 16:00 - 18:00 | S5. Lifelong bone health in Down syndrome: new research, new directions |
| 19:00 - 22:00 |
Welcome Reception
|
|
Room 3
|
|
|---|---|
| 8:30 - 9:00 |
Registration
|
| 9:00 - 10:30 | |
| 10:30 - 11:00 |
Break
|
| 11:00 - 13:00 | S3.The DS-Connect® Registry and the INCLUDE Collaboration for Down Syndrome Progress (CDP): Two Transformative Tools to Accelerate Participant-Centered Research |
| 13:00 - 14:00 |
Lunch and Networking
|
| 14:00 - 15:00 | |
| 15:00 - 16:00 | |
| 16:00 - 18:00 | S6. Innovative Engagement Methods and Communication Strategies for Promoting Down Syndrome Clinical Research Participation |
| 19:00 - 22:00 |
Welcome Reception
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Thursday, June 18, 2026
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Room 1
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Room 2
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Room 3
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| 8:30 - 9:30 | Conference: Dr. Leonard Abbeduto | ||
| 9:30 - 11:30 | S7. Amyloid-lowering Immunotherapies for Down Syndrome-related Alzheimer’s disease: Neuropathological Insights and Vascular Safety in Clinical Trials | S8. Research advances toward the treatment of obstructive sleep apnea in people with Down syndrome | S9. Transforming health outcomes for Down syndrome using Population Level Data |
| 11:30 - 12:00 |
Morning Break Thursday
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| 12:00 - 13:00 | Nanosymposium 1 | Nanosymposium 2 | Nanosymposium 3 |
| 13:00 - 14:00 |
Lunch and Networking Thursday
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||
| 14:00 - 16:00 | S10.Metabolic dysfunction and associated liver abnormalities in individuals with Down syndrome | S11. Executive Function in Down Syndrome Across the Lifespan: From Mechanisms to Modifiers of Alzheimer’s Disease Risk | S12. Industry Session |
| 16:00 - 18:00 | Posters and Happy Hour 1 | ||
| 18:00 - 19:00 | Conference: Dr. Mary McCarron | ||
|
Room 1
|
Room 2
|
|
|---|---|---|
| 8:30 - 9:30 | Conference: Dr. Leonard Abbeduto | |
| 9:30 - 11:30 | S7. Amyloid-lowering Immunotherapies for Down Syndrome-related Alzheimer’s disease: Neuropathological Insights and Vascular Safety in Clinical Trials | S8. Research advances toward the treatment of obstructive sleep apnea in people with Down syndrome |
| 11:30 - 12:00 |
Morning Break Thursday
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|
| 12:00 - 13:00 | Nanosymposium 1 | Nanosymposium 2 |
| 13:00 - 14:00 |
Lunch and Networking Thursday
|
|
| 14:00 - 16:00 | S10.Metabolic dysfunction and associated liver abnormalities in individuals with Down syndrome | S11. Executive Function in Down Syndrome Across the Lifespan: From Mechanisms to Modifiers of Alzheimer’s Disease Risk |
| 16:00 - 18:00 | Posters and Happy Hour 1 | |
| 18:00 - 19:00 | Conference: Dr. Mary McCarron | |
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Room 3
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|---|---|
| 8:30 - 9:30 | |
| 9:30 - 11:30 | S9. Transforming health outcomes for Down syndrome using Population Level Data |
| 11:30 - 12:00 |
Morning Break Thursday
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| 12:00 - 13:00 | Nanosymposium 3 |
| 13:00 - 14:00 |
Lunch and Networking Thursday
|
| 14:00 - 16:00 | S12. Industry Session |
| 16:00 - 18:00 | Posters and Happy Hour 1 |
| 18:00 - 19:00 |
|
Room 1
|
|
|---|---|
| 8:30 - 9:30 | Conference: Dr. Leonard Abbeduto |
| 9:30 - 11:30 | S7. Amyloid-lowering Immunotherapies for Down Syndrome-related Alzheimer’s disease: Neuropathological Insights and Vascular Safety in Clinical Trials |
| 11:30 - 12:00 |
Morning Break Thursday
|
| 12:00 - 13:00 | Nanosymposium 1 |
| 13:00 - 14:00 |
Lunch and Networking Thursday
|
| 14:00 - 16:00 | S10.Metabolic dysfunction and associated liver abnormalities in individuals with Down syndrome |
| 16:00 - 18:00 | Posters and Happy Hour 1 |
| 18:00 - 19:00 | Conference: Dr. Mary McCarron |
|
Room 2
|
|
|---|---|
| 8:30 - 9:30 | |
| 9:30 - 11:30 | S8. Research advances toward the treatment of obstructive sleep apnea in people with Down syndrome |
| 11:30 - 12:00 |
Morning Break Thursday
|
| 12:00 - 13:00 | Nanosymposium 2 |
| 13:00 - 14:00 |
Lunch and Networking Thursday
|
| 14:00 - 16:00 | S11. Executive Function in Down Syndrome Across the Lifespan: From Mechanisms to Modifiers of Alzheimer’s Disease Risk |
| 16:00 - 18:00 | Posters and Happy Hour 1 |
| 18:00 - 19:00 |
|
Room 3
|
|
|---|---|
| 8:30 - 9:30 | |
| 9:30 - 11:30 | S9. Transforming health outcomes for Down syndrome using Population Level Data |
| 11:30 - 12:00 |
Morning Break Thursday
|
| 12:00 - 13:00 | Nanosymposium 3 |
| 13:00 - 14:00 |
Lunch and Networking Thursday
|
| 14:00 - 16:00 | S12. Industry Session |
| 16:00 - 18:00 | Posters and Happy Hour 1 |
| 18:00 - 19:00 |
Friday, June 19, 2026
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Room 1
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Room 2
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Room 3
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| 8:30 - 9:30 | Conference: Juan Fortea | ||
| 9:30 - 11:30 | S13. Down Syndrome Regression Disorder: New Frontiers in Biomarkers, Phenotypes, and Clinical Trials | S14. Microbiome insights in Down Syndrome | S15. Advancing Knowledge on lifestyle factors in the context of Gene Overdosage and Early-Life Obesity in Down Syndrome, the legacy of GO-DS21. |
| 11:30 - 12:00 |
Morning Break Friday
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| 12:00 - 13:00 | Nanosymposium 4 | Nanosymposium 5 | Nanosymposium 6 |
| 13:00 - 14:00 |
Lunch and Network Friday
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| 14:00 - 16:00 | S16. Immune dysregulation in people with Down syndrome: From mechanisms to clinical trials | S17. Update on blood pressure regulation in Down syndrome - is it truly protective? | S18. Effective community engagement in older adults with Down syndrome: The ABC-DS experience |
| 16:00 - 18:00 | Posters and Happy Hour 2 | ||
| 18:00 - 19:00 | Conference: Dr. Sonja Rasmussen | ||
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Room 1
|
Room 2
|
|
|---|---|---|
| 8:30 - 9:30 | Conference: Juan Fortea | |
| 9:30 - 11:30 | S13. Down Syndrome Regression Disorder: New Frontiers in Biomarkers, Phenotypes, and Clinical Trials | S14. Microbiome insights in Down Syndrome |
| 11:30 - 12:00 |
Morning Break Friday
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| 12:00 - 13:00 | Nanosymposium 4 | Nanosymposium 5 |
| 13:00 - 14:00 |
Lunch and Network Friday
|
|
| 14:00 - 16:00 | S16. Immune dysregulation in people with Down syndrome: From mechanisms to clinical trials | S17. Update on blood pressure regulation in Down syndrome - is it truly protective? |
| 16:00 - 18:00 | Posters and Happy Hour 2 | |
| 18:00 - 19:00 | Conference: Dr. Sonja Rasmussen | |
|
Room 3
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|
|---|---|
| 8:30 - 9:30 | |
| 9:30 - 11:30 | S15. Advancing Knowledge on lifestyle factors in the context of Gene Overdosage and Early-Life Obesity in Down Syndrome, the legacy of GO-DS21. |
| 11:30 - 12:00 |
Morning Break Friday
|
| 12:00 - 13:00 | Nanosymposium 6 |
| 13:00 - 14:00 |
Lunch and Network Friday
|
| 14:00 - 16:00 | S18. Effective community engagement in older adults with Down syndrome: The ABC-DS experience |
| 16:00 - 18:00 | Posters and Happy Hour 2 |
| 18:00 - 19:00 |
|
Room 1
|
|
|---|---|
| 8:30 - 9:30 | Conference: Juan Fortea |
| 9:30 - 11:30 | S13. Down Syndrome Regression Disorder: New Frontiers in Biomarkers, Phenotypes, and Clinical Trials |
| 11:30 - 12:00 |
Morning Break Friday
|
| 12:00 - 13:00 | Nanosymposium 4 |
| 13:00 - 14:00 |
Lunch and Network Friday
|
| 14:00 - 16:00 | S16. Immune dysregulation in people with Down syndrome: From mechanisms to clinical trials |
| 16:00 - 18:00 | Posters and Happy Hour 2 |
| 18:00 - 19:00 | Conference: Dr. Sonja Rasmussen |
|
Room 2
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|
|---|---|
| 8:30 - 9:30 | |
| 9:30 - 11:30 | S14. Microbiome insights in Down Syndrome |
| 11:30 - 12:00 |
Morning Break Friday
|
| 12:00 - 13:00 | Nanosymposium 5 |
| 13:00 - 14:00 |
Lunch and Network Friday
|
| 14:00 - 16:00 | S17. Update on blood pressure regulation in Down syndrome - is it truly protective? |
| 16:00 - 18:00 | Posters and Happy Hour 2 |
| 18:00 - 19:00 |
|
Room 3
|
|
|---|---|
| 8:30 - 9:30 | |
| 9:30 - 11:30 | S15. Advancing Knowledge on lifestyle factors in the context of Gene Overdosage and Early-Life Obesity in Down Syndrome, the legacy of GO-DS21. |
| 11:30 - 12:00 |
Morning Break Friday
|
| 12:00 - 13:00 | Nanosymposium 6 |
| 13:00 - 14:00 |
Lunch and Network Friday
|
| 14:00 - 16:00 | S18. Effective community engagement in older adults with Down syndrome: The ABC-DS experience |
| 16:00 - 18:00 | Posters and Happy Hour 2 |
| 18:00 - 19:00 |
Saturday, June 20, 2026
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Room 1
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Room 2
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Room 3
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|---|---|---|---|
| 8:30 - 10:30 | S19. Aging with Down syndrome | S20. Unraveling Risk and Resilience: The Role of Co-Occurring Health Conditions in Down Syndrome-Associated Alzheimer’s Disease | S4. Hearing and Vestibular Sequelae in Down Syndrome |
| 10:30 - 11:00 |
Morning Break Saturday
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| 11:00 - 13:00 |
Science and Society I
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| 13:00 - 14:00 |
Lunch and Networking Saturday
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| 14:00 - 16:00 |
Science and Society II
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| 16:00 - 18:00 |
Afternoon Break Saturday
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||
|
Room 1
|
Room 2
|
|
|---|---|---|
| 8:30 - 10:30 | S19. Aging with Down syndrome | S20. Unraveling Risk and Resilience: The Role of Co-Occurring Health Conditions in Down Syndrome-Associated Alzheimer’s Disease |
| 10:30 - 11:00 |
Morning Break Saturday
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|
| 11:00 - 13:00 |
Science and Society I
|
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| 13:00 - 14:00 |
Lunch and Networking Saturday
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| 14:00 - 16:00 |
Science and Society II
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| 16:00 - 18:00 |
Afternoon Break Saturday
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|
Room 3
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|---|---|
| 8:30 - 10:30 | S4. Hearing and Vestibular Sequelae in Down Syndrome |
| 10:30 - 11:00 |
Morning Break Saturday
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| 11:00 - 13:00 |
Science and Society I
|
| 13:00 - 14:00 |
Lunch and Networking Saturday
|
| 14:00 - 16:00 |
Science and Society II
|
| 16:00 - 18:00 |
Afternoon Break Saturday
|
|
Room 1
|
|
|---|---|
| 8:30 - 10:30 | S19. Aging with Down syndrome |
| 10:30 - 11:00 |
Morning Break Saturday
|
| 11:00 - 13:00 |
Science and Society I
|
| 13:00 - 14:00 |
Lunch and Networking Saturday
|
| 14:00 - 16:00 |
Science and Society II
|
| 16:00 - 18:00 |
Afternoon Break Saturday
|
|
Room 2
|
|
|---|---|
| 8:30 - 10:30 | S20. Unraveling Risk and Resilience: The Role of Co-Occurring Health Conditions in Down Syndrome-Associated Alzheimer’s Disease |
| 10:30 - 11:00 |
Morning Break Saturday
|
| 11:00 - 13:00 |
Science and Society I
|
| 13:00 - 14:00 |
Lunch and Networking Saturday
|
| 14:00 - 16:00 |
Science and Society II
|
| 16:00 - 18:00 |
Afternoon Break Saturday
|
|
Room 3
|
|
|---|---|
| 8:30 - 10:30 | S4. Hearing and Vestibular Sequelae in Down Syndrome |
| 10:30 - 11:00 |
Morning Break Saturday
|
| 11:00 - 13:00 |
Science and Society I
|
| 13:00 - 14:00 |
Lunch and Networking Saturday
|
| 14:00 - 16:00 |
Science and Society II
|
| 16:00 - 18:00 |
Afternoon Break Saturday
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