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S7. Amyloid-lowering Immunotherapies for Down Syndrome-related Alzheimer’s disease: Neuropathological Insights and Vascular Safety in Clinical Trials

Tracks
Room 1
Thursday, June 18, 2026
9:30 - 11:30
Room 1

Speaker

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Dr. Lisi Flores Aguilar
Postdoctoral Scholar
University of California, Irvine

Neuropathology of the blood-brain barrier across the AD continuum in Down syndrome: implications for amyloid lowering therapies.

Biography

Donna M Wilcock

Biomarkers and vascular burden in DS: tools to inform safety and clinical trial readiness.

Biography

Javier Arranz

Clinical perspectives and case reports: understanding safety and indications of anti-amyloid therapies in DS.

Biography

Prof. Michael Rafii
Keck School Of Medicine Of USC

Amyloid-immunotherapy clinical trials in Down syndrome: design, safety considerations, and lessons for the field.

Biography

Dr. Isabel Barroeta
Faculty Neurologist
HOSPITAL DE LA SANTA CREU I SANT PAU (Centre CERCA)

Title to be determined

Biography

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