Organizers:
Ana Paula Dantas. University of Barcelona, Spain
Luca Liberale. ESCI COUNCIL – University of Genoa, Italy
Assisted by:
Aldo Bonaventura. ESCI YOUNG RESEARCHERS COUNCIL, Varese, Italy

Wednesday June 5, 2024

13:30h – 15:00h

SYMPOSIUM 8.1 | NEURO
Chairpersons: Luca Liberale (Genoa, Italy) & Markus Sperandio (Munich, Germany)

G9a, a histone lysine methyltransferase associated with age-related cognitive decline and neuropsychiatric disorders
Christian Griñan Ferrè. Pharmacy School, University of Barcelona, Barcelona, Spain

Next generation cell therapy for stroke
Ruslan Rust. Keck School of Medicine of University of Southern California, California, United States

TDP-43 controls angiogenesis and blood-brain barrier integrity 
Eloi Montañez Miralles. Department of Physiological Sciences,University of Barcelona, Barcelona, Spain

15:00h – 15:30h

COFFEE BREAK

15:30h – 17:00h

SYMPOSIUM 8.2 | GENDER AND AGING
Chairpersons: Aldo Bonaventura (Varese, Italy) & Simon Kraler (Zurich, Switzerland)

Aging and sex differences on miRNA modulation in experimental acute myocardial infarction
Susana Novella. Incliva Health Institute, University of Valencia Medical School, Valencia, Spain

Aging-associated changes in the regulation of vascular function: does sex matter?
Ana Paula Dantas. Medical School, University of Barcelona, Barcelona, Spain

Abstract 1: Gender differences in the correlation between PCSK9 and clinical outcomes in hemodialysis patients 
Valeria Cugno. University of Genoa, Génova, Italy

Abstract 2: Cardiac aging trajectory is altered in the offspring born to maternal obesity in a sex-dependent way 
Luis Grilo. CNC-UC, Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal

17:00h – 17:30h

OPENING CEREMONY

17:30h-18-30h

OPENING LECTURE

Epigenetics in Health and Disease: From Knowledge to Applications
Manel Esteller. Barcelona, Spain

18:30h - 19:30h

SATELLITE SYMPOSIUM FICYE | MEDITERRANEAN DIET, BEER AND HEALTH

Chairperson: Lina Badimon (Barcelona, Spain)

**The Forum for Beer and Lifestyle Research (FICYE) is an entity that promotes research on beer and its relationship with lifestyle**

Ageing and nutrition: delaying chronological age by improving physiological age

Lina Badimon. Molecular Pathology and Therapeutics Department, IR-Hospital de Sant Pau, Barcelona, Spain

Beer, nutrition and immunity

Ascensión Marcos. Malaga Biomedical Research Institute and Nanomedicine Platform (IBIMA)

Gut microbiota, beer and diet

Isabel Moreno. Malaga Biomedical Research Institute and Nanomedicine Platform (IBIMA)

19:30-21.00h

BEER TASTING AND CHAMPIONS LEAGUE UNIVERSITIES

Thursday June 6, 2024 

8:15h – 9:00h

PAS GRAS OUTREACH ACTIVITY 

9:00h – 10:30h

SYMPOSIUM 8.3 | CARDIO
Chairpersons: Ana Paula Dantas (Barcelona, Spain) & Alessandra Vecchiè (Varese, Italy)

Accelerated cardiovascular disease in Hutchinson-Gilford progeria syndrome: new mechanisms and candidate therapies 
Vincente Andres. Spanish National Center for Cardiovascular Research (CNIC), Madrid, Spain

Molecular prospective on aging: unrevealing inflammation in cerebrovascular diseases 
Luca Liberale. Dept of Medicine, University of Genoa, Genova, Italy

The role of aging and comorbidities on myocardial remodelling and HFpEF management 
Angela Sciacqua. Geriatric Division – Mater Domini University Hospital, Catanzaro, Italy

10:30h – 11:00h

COFFEE BREAK

11:00h – 12:30h

SYMPOSIUM 8.4 | CARDIO
Chairpersons: Fabrizio Montecucco (Genoa, Italy) & Ana Paula Dantas (Barcelona, Sapin)

The Janus face of O-GlcNAcylation: When does adaptation become pathological 
Cameron McCarthy. University of South Carolina School of Medicine Columbia, Columbia, USA

Prognostic role of serum albumin in heart failure: a focus on elderly people 
Aldo Bonaventura. Ospedale di Circolo Fondazione Macchi, Varese, Italy

Abstract 1: An integrative systems biology approach for deciphering athero-resilience of the internal mammary artery in aging
Yifan Wang. Center For Molecular Cardiology, University of Zurich, Zurich, Switzerland

Abstract 2: The Osteopontin orchestra: association with neutrophil functions via defined pathways in atherosclerosis and cardiovascular risk 
Davide Ramone. University of Genoa, Génova, Italy

12:30h -13:30h

POSTER SESSION

13:30h - 14:30h

LUNCH

14:30h - 16:00h

SYMPOSIUM 8.5 | ONCO
Chairpersons: Luca Liberale (Genoa, Italy) & Aldo Bonaventura (Varese, Italy)

Telomerase activation for the treatment of age-related diseases and telomere syndrome 
Paula Martínez. Centro Nacional de Investigaciones Oncológicas (CNIO).           Madrid, Spain

Targeting the instrinsic apoptosis pathway: a window of opportunity for cancer age-related disease treatment
Joan Montero. University of Barcelona, Barcelona, Spain

Abstract 1: Skin ageing induced by y-irradiation - The impact of targeting mitochondria with naturally-occurring polyphenols on mitochondrial bioenergetic and redox homeostasis
José Texeira. University of Coimbra, Coimbra, Portugal

Abstract 2: Osteopontin levels are associated with neutrophil extracellular trap formation in elderly patients with severe sepsis 
Alessandro Scuricini. University of Génova, Génova, Italy

Friday, June 7 2024 

9:00h – 10:30h

SYMPOSIUM 8.6 | IMMUNO
Chairpersons: Aldo Bonaventura (Varese, Italy) & Gemma Vilahur (Barcelona, Spain)

Longevity Pharmacology Comes of Age 
Joao Pedro de Magalhães. Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK

Perinatal maturation of innate immunity: the role of neutrophils
Markus Sperandio. Institute for Cardiovascular Physiology and Pathophysiology, Ludwig-Maximilians-Universität München

Abstract 1: Softening the aging mind: the impact of tissue mechanics in neuronal cell metabolism modulation
Heloísa Gerardo. University of Coimbra, Coimbra, Portugal

Abstract 2: Circulating Extracellular Vesicles from Patients with Chronic Myocardial Infarction Modifies the Phenotype of Endothelial Cellsand Fibroblasts
Francisco Javier Jiménez-Trinidad. University of Barcelona, Barcelona, Spain

10:30h – 11:00h

COFFEE BREAK

12:30h - 14:00h

LUNCH

14:00h - 14:30h

EDITOR IN CHIEF EJCI / AWARD BEST ARTICLES EJC

14:30h - 15:30h

ESCI AWARDS

15:30h - 16:30h

ALBERT STRUYVENBERG MEDAL TO PROF. VALENTIN FUSTER AND LECTURE AWARD

16:30h - 17:00h

CLOSING