Organizers: 

Ángel Raya - Bellvitge Biomedical Research Institute (IDIBELL), Barcelona (Spain)
Federico Carbone. ESCI Council – IRCCS Hospital San Martino, Genoa, Italy
Assisted by:
Deeksha Malhan. ESCI Young Researchers Council – MSH Medical School Hamburg, Germany

Wednesday June 5, 2024

13:30h – 15:00h

SYMPOSIUM 5.1 | CLINICAL TRANSLATION OF CELL THERAPY FOR REGENERATIVE MEDICINE
Chairpersons: Federico Carbone (Genoa, Italy) & Deeksha Malhan (Hamburg, Germany)

Making and repairing hearts with human pluripotent stem cells
Robert Zweigerdt. MH, Hannover, Germany

Microvascular network support of thick tissue engineered cardiac constructs 
Ángel Raya. IDIBELL, Barcelona, Spain 

Abstract 1: Development of Tissue-Engineered Cell-Laden Vascular Grafts with Micro/Nano Topographical Cues from Human Induced Pluripotent Stem Cell Derivatives
Jagoda Litowczenko. Nanobiomedical Centre, Adam Mickiewicz University, Poznan, Poland

Abstract 2: A pathologically validated deep learning model for laryngeal and hypopharyngeal tumor segmentation on MRI
Koen Kuijer. University Medical Center Utrecht, The Netherlands

15:00h – 15:30h

COFFEE BREAK

15:30h – 17:00h

SYMPOSIUM 5.2 | HARNESSING ADULT STEM CELLS FOR EFFICIENT REGENERATION
Chairpersons: Deeksha Malhan (Hamburg, Germany) & Ángel Raya (Barcelona, Spain)

Macrophages crosstalk with intestinal epithelial cells to regulate regeneration 
Jordi Guiu. IDIBELL, Barcelona, Spain

Probiotic as emerging strategy to counteract BPA metabolic toxicity: insight from in vivoand in vitro studies 
Oliana Carnevali. PU Marche, Ancona, Italy

Abstract 1: Effects of the chemopreventive polyphenol "CURcumin" and its derivative "VANillin" on tumor-associated inflammation and tumor metabolism 
Zeinab El Rashed. IRCCS OSP. Policlinico San Martino. Genoa, Italy

17:00h – 17:30h

OPENING CEREMONY

17:30h-18-30h

OPENING LECTURE

Epigenetics in Health and Disease: From Knowledge to Applications
Manel Esteller. Barcelona, Spain

18:30h - 19:30h

SATELLITE SYMPOSIUM FICYE | MEDITERRANEAN DIET, BEER AND HEALTH

Chairperson: Lina Badimon (Barcelona, Spain)

**The Forum for Beer and Lifestyle Research (FICYE) is an entity that promotes research on beer and its relationship with lifestyle**

Ageing and nutrition: delaying chronological age by improving physiological age

Lina Badimon. Molecular Pathology and Therapeutics Department, IR-Hospital de Sant Pau, Barcelona, Spain

Beer, nutrition and immunity

Ascensión Marcos. Malaga Biomedical Research Institute and Nanomedicine Platform (IBIMA)

Gut microbiota, beer and diet

Isabel Moreno. Malaga Biomedical Research Institute and Nanomedicine Platform (IBIMA)

19:30-21.00h

BEER TASTING AND CHAMPIONS LEAGUE UNIVERSITIES

Thursday June 6, 2024 

8:15h – 9:00h

PAS GRAS OUTREACH ACTIVITY

9:00h – 10:30h

SYMPOSIUM 5.3 | iPSC-BASED MODELING OF EARLY TRANSFORMATION EVENTS
Chairpersons: Federico Carbone (Genoa, Italy) & Deeksha Malhan (Hamburg, Germany)

iPSC-based modeling of tumors of the peripheral nervous system
Eduard Serra. IGTP, Barcelona, Spain
 
CRISPR-based modeling to study genetic predisposition to myelodysplastic syndromes 
Alessandra Giorgetti. IDIBELL, Barcelona, Spain

Abstract 1: Integrative analysis identifies potential colorectal cancer biomarkers in the circulating blood of obese patients 
Jesús Pilo. IBIMA Plataforma BIONAND-UMA, Málaga, Spain

Abstract 2: Developing an iPSC-based MSH2-deficient in vitro model as a platform to characterize early molecular events driving brain gliomas in Constitutional-MisMatch-Repair-Deficiency (CMMRD)-syndrome 
Manuel Torralba. IDIBELL, Barcelona, Spain

10:30h – 11:00h

COFFEE BREAK

11:00h – 12:30h

SYMPOSIUM 5.4 | THE CIRCADIAN CLOCK IN HEALTH AND DISEASE
Chairpersons: Ángel Raya (Barcelona, Spain) & Federico Carbone (Genoa, Italy)

Circadian Medicine: Aligning Circadian Rhythms and Treatment Timing for Enhanced Chemotherapy 
Ángela Relogio. Charité - Universitätsmedizin, Berlin, Germany

Epidermal clock integration and gating of brain signals as a guarantor of skin homeostasis 
Thomas Mortimer. IRB, Barcelona, Spain

Abstract 1: PARP Inhibitor-Induced Circadian Rhythm Alterations in Ovarian Cancer Patients: Correlation with Treatment Side Effects
Deeksha Malhan. MSH Medical School Hamburg, Germany

Abstract 2: CytoMARK: Development of a non-invasive in vitro diagnostics for endometrial cancer using cervical fluids
Irene de la Calle. Vall D'hebron Institute of Research, Barcelona, Spain

12:30h -13:30h

POSTER SESSION

13:30h - 14:30h

LUNCH

14:30h - 16:00h

SYMPOSIUM 5.5 | CLINICAL APPLICATION OF DIRECTED GENOME EDITION
Chairpersons: Leonilde Bonfrate (Bari, Italy) & Ángel Raya (Barcelona, Spain)

Personalized genome editing approaches to precisely correct Fanconi anemia mutations
Paula Rio. CIEMAT, Madrid, Spain

Programming gene expression by targeted epigenetic editing
Angelo Lombardo. SR-Tiget, Milan, Italy

Abstract 1: Guadecitabine impact on phenotype and function of peripheral blood and hematopoietic stem cell-derived NK in vitro differentiation and proliferation
Mariangela Petito. IRCCS Ospedale Policlinico San Martino, Genova, Italy

Abstract 2: Studying cellular memory in response to intestinal injury 
Borja Arozamena. IDIBELL, Barcelona, Spain

Friday, June 7 2024 

9:00h – 10:30h

SYMPOSIUM 5.6 | THE NEXT FRONTIERS IN GENE EDITING
Chairpersons: Ángel Raya (Barcelona, Spain)

Unlocking gene editing - applications, pitfalls and lessons learned
Toni Cathomen. University of Freiburg, Germany

Gene writing in mammalian cells and novel strategies for in vivo delivery
Marc Güell. UPF, Barcelona, Spain

Abstract 1: Ways to improve impaired metabolism in MPAN patients - is there a hope for pharmacological intervention based on an in vitro study
Agata Wydrych. Nencki Institute, Warsaw, Poland

Abstract 2: An NSG-MHC I/II DKO mouse as a xenograft model to evaluate the long-term antitumor response of a hydrodynamically-injected EpCAM/CD3 BiTE 
Adrián Gil-Korilis. Cima Universidad de Navarra, Pamplona, Spain

10:30h – 11:00h

COFFEE BREAK

12:30h - 14:00h

LUNCH

14:00h - 14:30h

EDITOR IN CHIEF EJCI / AWARD BEST ARTICLES EJC

14:30h - 15:30h

ESCI AWARDS

15:30h - 16:30h

ALBERT STRUYVENBERG MEDAL TO PROF. VALENTIN FUSTER AND LECTURE AWARD

16:30h - 17:00h

CLOSING