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S4 Program (Gut, Liver, Microbiota & Lifestyle)


Organizers: 
José Manuel Fernández-Real. Faculty of Medicine Hospital Girona, Spain
Piero Portincasa. ESCI Trust– Internal Medicine, University of Bari, Policlinico Hospital, Bari, Italy
Marcin Krawczyk. ESCI Council - Hospital University Saarland, Homburg, Germany
Harshitha Shanmugam. ESCI Young Researchers Council – University of Bari, Italy



Wednesday June 5, 2024

13:30h – 15:00h

SYMPOSIUM 4.1
THE GUT-LIVER-BRAIN AXIS: EMERGING ASPECTS
Chairpersons: Marcin Krawczyk

Treating MASLD 2024. One, None or 100k? 
Piero Portincasa. Internal Medicine, University of Bari, Policlinico Hospital, Bari, Italy

The role of genetics in MASLD
Marcin Krawczyk. Hospital University Saarland, Homburg, Germany

What does the microbiota look like in NAFLD patients diagnosed with SIBO?
Anna Gudan. Department of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, Poland

Obesity and Diabetes: Gut-Brain axis and therapies
Gabriella Garruti. Section of Endocrinology, Andrology and Metabolic Diseases, Department of Emergency and Organ Transplants, University of Bari Medical School, Italy

15:00h – 15:30h

COFFEE BREAK


15:30h – 17:00h

SYMPOSIUM 4.2
THE PATHOPHYSIOLOGY OF MASLD: NEW APPROACHES ON FATTY LIVER DISEASE
Chairpersons: Francisco José Ortega 

Powering Therapeutic Breakthroughs: Mitochondria and MASLD
Malu Martínez-Chantar. Center for Cooperative Research in Biosciences (CIC bioGUNE), Spain

Unveiling the lipid metabolism deregulation in MetALD
Raquel Benedé-Ubieto. Universidad Complutense de Madrid, Spain

Abstract 1: The Role of Adiponectin in Liver Cirrhosis: A Systematic Review and Meta-analysis 
Abdulrahman Ismaiel. 

Abstract 2: Reprogramming macrophages to improve alcoholic steatohepatitis inflammatory phenotype 
Elena Lavado-Fernández. 

17:00h – 17:30h

OPENING CEREMONY


17:30h-18-30h

OPENING LECTURE

Epigenetics in Health and Disease: From Knowledge to Applications
Manel Esteller. Barcelona, Spain

18:30h - 19:30h

SATELLITE SYMPOSIUM FICYE | MEDITERRANEAN DIET, BEER AND HEALTH

**The Forum for Beer and Lifestyle Research (FICYE) is an entity that promotes research on beer and its relationship with lifestyle**

Ageing and nutrition: delaying chronological age by improving physiological age

Lina Badimon. Molecular Pathology and Therapeutics Department, IR-Hospital de Sant Pau, Barcelona, Spain

Beer, nutrition and immunity

Ascensión Marcos. Malaga Biomedical Research Institute and Nanomedicine Platform (IBIMA)

Gut microbiota, beer and diet

Isabel Moreno. Malaga Biomedical Research Institute and Nanomedicine Platform (IBIMA)


19:30-21.00h

BEER TASTING AND CHAMPIONS LEAGUE UNIVERSITIES



Thursday June 6, 2024 

8:15h – 9:00h

PAS GRAS OUTREACH ACTIVITY 

9:00h – 10:30h

SYMPOSIUM 4.3 | 
CUTTING-EDGE MODELS IN DROSOPHILA FOR STUDYING HOST-MICROBIOTA INTERACTIONS
Chairpersons:
 Anna Castells Nobau

Bacterial influence on host response to malnutrition: A multi-model species perspective
Renata Matos. Institute Ens De Lyon - Institute Genomics Functional De Lyon, France

The microbiome-gut-brain axis in Drosophila melanogaster
Omry Koren. Bar-Ilan University, Israel

Abstract 1: Electrophysiological protective properties of the natural formulation polyprotect (Neobianacid®) on cellular models of intestinal barriers
Mohamad Khalil.

Abstract 2: Gastrointestinal symptoms and misdiagnoses in Lebanese and Italian individuals with Familial Mediterranean Fever 
Nour Jaber. 


10:30h – 11:00h

COFFEE BREAK


11:00h – 12:30h

SYMPOSIUM 4.4 | 
NOUTRISHING INSIGHTS: DECODING GUT MICROBIAL METABOLISM IN MASLD ACROSS MALNUTRITION, FROM UNDERNUTRITION TO OVERNUTRITION
Chairpersons: José Manuel Fernández-Real

Oral microbiota a new risk factor for the development of cardio-metabolic diseases in human 
Vincent Blasco. Institut National de la Santé et de la Recherche Médicale (INSERM), France

How Microbial Metabolites affect cardiometabolic health: from NAFLD to atherosclerosis
Massimo Federico. University of Rome Tor Vergata, Italy


Abstract 1: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Assessing Cardiovascular Risk Factors and the Impact of Mediterranean Diet 
Ewa Awada. 

Abstract 2: Nutritional and Physiological Properties of Thymbra spicata: In Vitro Study Using Fecal Fermentation model and Intestinal Integrity by Ussing Chamber 
Laura Mahdi. 

12:30h -13:30h

POSTER SESSION

13:30h - 14:30h

LUNCH


14:30h - 16:00h

SYMPOSIUM 4.5 | 
PORTAL CIRCULATION AND BIOCHEMISTRY: A PORTAL TO PERSONALIZED LIVER MEDICINE?
Chairpersons: Piero Portincasa

Gut microbiota-derived factors and development of early portal hypertension in steatotic liver disease 
Gyorgy Baffy. Harvard Medical School, Boston University, Boston Healthcare System, USA

Current diagnostic tools for the assessment of liver dysfunction 
Katarzyna Kozłowska-Petriczko. Endoscopy Unit, SONOMED Medical Centre, Department of Translational Medicine, Pomeranian Medical University Szczecin, Poland


Abstract 1: Anti-Diabetic Drugs: Shaping the Protein Messages of the Diabetogenic Gut Derived Extracellular Vesicles 
Estefanía Torrejón.

Abstract 2: Intestinal Extracellular Vesicles: A Contribution to the Pathogenesis of Metabolic Associated Steatotic Liver disease 
Akiko Teshima. 

Abstract 3: Physical Inactivity and liver steatosis: Relationship between Sedentary Lifestyle and Metabolic Markers in different Genders
Jerlin Stephy JohnBritto.



Friday, June 7 2024 

9:00h – 10:30h

SYMPOSIUM 4.6 |
THE IMPACT OF BACTERIAL ENDOTOXIN ON LIVER METABOLISM
Chairpersons: Remy Burcelin

Intestinal barrier dysfunction and bacterial endotoxin in metabolic dysfunction-associated steatotic liver disease (MASLD) 
Ina Bergheim. University of Vienna, Austria

The possible role of lipopolysacharide binding protein in metabolic dysfunction-associated steatotic liver disease (MASLD) 
José Maria Moreno. Girona Biomedical Research Institute (IDIBGI), Spain

Abstract 1: Ramadan fasting generates better metabolic effects than a traditional intermittent fasting
Hala Abdallah.

Abstract 2: Exploring the Physiological Interactions and Nutritional Significance of Apulian Varieties of Cucumis melo: Implications for Gastrointestinal Health and Food Perception
Valeria Perniola.

10:30h – 11:00h

COFFEE BREAK

11:00h – 12:30h

SYMPOSIUM 4.7 | LIVER METAGENOMICS AND OTHER OMICS
Chairperson:
 Jordi Mayneris

Understanding the impact of nutritional status on the microbiota-gut-liver axis
Jonathan Shann. University of Southampton, United Kingdom

Potential Therapeutic Implications of Histidine Catabolism by the Gut Microbiota in Metabolic Diseases
Xavier Escoté. Technology Centre of Catalonia – Eurecat, Spain


Abstract 1: Six-month gallstone Incidence after Sleeve Gastrectomy in Lebanese obese patients. Room for prevention 
Mariyana Samhat.

12:30h - 14:00h

LUNCH

14:00h - 14:30h

EDITOR IN CHIEF EJCI / AWARD BEST ARTICLES EJC

14:30h - 15:30h

ESCI AWARDS

15:30h - 16:30h

ALBERT STRUYVENBERG MEDAL TO PROF. VALENTIN FUSTER AND LECTURE AWARD

16:30h - 17:00h

CLOSING

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